Top 6 Fictional Scary Diseases That Does Not Exist

Michael Caine
Michael Caine
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There are some fictional diseases, which are discovered from some famous books, movies, games, or manga but do not exist in this real world. The signs and symptoms of these diseases are almost real and scary. Today we’ll discuss them.

Top 6 Fictional Diseases


A virus that began life in wolves two thousand years ago. Genghis Khan was the first to become infected. It causes the typical symptoms of vampirism, such as photosensitivity and invincibility. Except for a few feral children, the entire country of Russia is infected. The virus can cause extreme mutations, such as the snake’s tail found in Khan’s head scientist.

fictional diseases

Hanahaki Disease

The Hanahaki Disease is a fictional disease caused by unrequited or unaccepted love in which the patient’s throat fills up with flower petals, which they then throw and cough up (sometimes even the flowers). One of the only ways for the disease to ‘disappear’ is if the person returns the feeling (it cannot be resolved through friendship; it must be genuine feelings of love). The infection can also be removed surgically, but the feelings vanish along with the petals. If they choose the negative options, or if the feeling is not returned in time, the patient’s lungs will fill with flowers and he or she will suffocate.

Dragon Fox

Dragon pox is a contagious, potentially fatal disease that affects wizards and witches. Its symptoms are likely to be similar to those of Muggle illnesses such as smallpox and chickenpox. Dragon pox, on the other hand, causes a greenish tinge to the victim’s skin in addition to leaving it pockmarked. Simpler cases include a green-and-purple rash between the toes and sparks coming out of the patient’s nostrils when he or she sneezes. Elderly patients appear to be more susceptible to dragon pox than younger patients. Gunhilda of Gorsemoor discovered a cure for dragon pox, but the disease has not been completely eradicated, as evidenced by the Magical Bugs ward at St. Mungo’s Hospital.

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Great Plague

During the mid-1600s of the Third Age of the Sun, a mysterious disease swept through every kingdom in Middle-earth. The origins of the Plague are unknown, except that it may have been contracted from the Corsairs who attacked Gondor in the Third Age of 1634, two years before the Plague occurred. The Plague killed nearly all of Middle-inhabitants, earth especially in Gondor and the North. It is inspired by the Black Death.

Plague of Insomnia

Rebeca, the adopted daughter of José Arcadio Buenda and rsula Iguarán, brought an epidemic into the Buenda household and the town of Macondo. This plague, which originated in the northern Indian kingdoms of La Guajira (Colombia), is distinguished by symptoms such as wide-open, glowing eyes like those of a cat, and the inability to sleep. Those infected (in the novel, the entire town of Macondo) experience no tiredness or sleepiness and can thus work all hours of the day and night. However, as time passes, those infected begin to lose all of their memories and knowledge of the world, eventually leaving them in a state where they have forgotten the names and uses of everything, as well as their own identities. The plague is widely regarded as one of the most prominent examples of magical realism in Garc Márquez’s works.


During their school days in Llandaff, Roald Dahl’s friend Thwaites invented a fictional disease. Thwaites made this up to amuse Roald and his friends, but he claims his father told him about the disease, which can be contracted by eating liquorice bootlaces. According to Thwaites, the bootlaces contain rat blood rather than licquorice, and they are made this way by rat-catchers bringing their rats to the sweet factory, where they are ground into a paste and mashed up to form licquorice bootlaces. Thwaites warned Roald and his friends not to eat them because a rat’s tail would burst out of their buttocks and their teeth would turn into fangs if they did. Only Roald and his friends recognized the joke, which Thwaites took with deadpan humor.


All the fictional diseases are quite scary. But they do not exist in the real world, so we don’t have to worry about them. Although the creator of these diseases are so creative and they deserve some appreciation from us.

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